To date - the only problem has been NOD32 - When I went to install it (this is what I had on Vista), Windows 7 told me it had compatibility issues. The Windows Easy Transfer had transferred the NOD32 plugin into Outlook just fine because when I re-installed Microsoft Office 2007, the plugin was there. On ESET's site they do not seem to have any information on version 3, they seem to be pushing 4 and mention that they seem to say that they are not providing support on 7 until it releases. I have run AVG and and AVAST and they both clearly state that they support 7. FYI.