I have been using roaming profiles with between my different machines: My Home PC a Windows 7 32 bit machine, my Laptop, a Windows 7 64 bit machine, and a Virtual Machine, a Windows 7 32 bit machine. All works really well except a couple of problems with shortcuts and applications:
1. Google apps. This really was bugging me because Google apps like to install in the Current user mode, and also puts settings different for 32bit vs. 64 bit - program files vs progam files(x86) - What I did was copy the folder in the 64 bit folder also to the x86 - that seem to fix it ( I know it was stupid fix, but it works)
2. Dropbox - this is a little more frustrating, but Dropbox also sets up in the current user mode so I have to set the dropbox folder to a common location like the root of c: and then relink each dropbox session.
I will keep this entry updated as I find problems.